Why do AstraZeneca Covid jab victims only have a 3-year cut-off for ... trends now

Why do AstraZeneca Covid jab victims only have a 3-year cut-off for ... trends now
Why do AstraZeneca Covid jab victims only have a 3-year cut-off for ... trends now

Why do AstraZeneca Covid jab victims only have a 3-year cut-off for ... trends now

AstraZeneca's Covid vaccine – once heralded as a 'triumph for science' – is being withdrawn worldwide. 

The jab, developed with Oxford University, can no longer be used in the European Union after the company voluntarily pulled its 'marketing authorisation', coming into effect today.

Similar applications to withdraw the vaccine will be made in other countries which had previously approved it, including the UK. Around 50million doses were given in Britain. 

While credited with saving more than 6million lives, the jab — known as Vaxzevria — has come under intense scrutiny in recent months over a rare but fatal side effect. 

In February, the pharmaceutical titan admitted in documents lodged with the High Court that it 'can, in very rare cases, cause thrombocytopenia syndrome (TTS)'. 

So why has the jab now been withdrawn? Are you at risk if you had Vaxzevria? And what do you have to prove if you have been injured by the AstraZeneca vaccine? 

Here, MailOnline explains everything you need to know. 

The graph shows the cumulative number of Covid jabs dished out in the UK since the pandemic began, the percentage of each age group which has had a jab (bottom left) and the number of each Covid vaccine brand dished out

The graph shows the cumulative number of Covid jabs dished out in the UK since the pandemic began, the percentage of each age group which has had a jab (bottom left) and the number of each Covid vaccine brand dished out

Why has it been withdrawn? 

Fifty-one families are currently pursuing legal action against AstraZeneca, arguing its 'defective' jab was to blame for their injuries and deaths of loved ones. 

However, the Cambridge-based drug manufacturer denies the decision to withdraw the vaccine is related to the court case. Instead, it insists Vaxzevria is being removed from markets for commercial reasons.

The company said in court documents that the vaccine is reportedly no longer being manufactured or supplied, having been superseded by updated vaccines that tackle newer variants.

In a statement today, the company said: 'According to independent estimates, over 6.5million lives were saved in the first year of use alone and over three billion doses were supplied globally.

AstraZeneca's Covid jab timeline 

January 2020: Oxford University scientists start working on a Covid vaccine after the World Health Organization declares the spread of the virus a 'Public Health Emergency of International Concern'

March 2020: Then Prime Minister Boris announced the first national lockdown. That same month, the Government invests £88million in the development of the Oxford vaccine

 April 2020: Alongside AstraZeneca, scientists start the first clinical trials of their new vaccine. This involved 1,000 volunteers in the UK

July 2020: Results from phase two trials of AstraZeneca's jab are published

4 December 2020: Covid jab rollout begins with the Pfizer vaccine. Over-80s and care home workers are given priority

8 December 2020:  Phase three trial results of the AstraZeneca's jab are published. These are what health officials will use to approve the jab for use in the UK

30 December 2020: AstraZeneca's jab is approved for emergency use

4 January 2021: First AstraZeneca doses start being dished out. Brian Pinker, 82, is the first person to receive the jab outside of clinical trials

8 January 2021: Frontline NHS staff start being offered vaccines 

8 February 2021: Over-70s are called forward

14 February 2021: Roll-out opens up to Brits with underlying heath conditions, as well as the over-65s

28 February 2021: All over-60s are invited for jabs

11 March 2021: European countries start suspending use of the AstraZeneca jab after death of a 60-year-old woman from a blood clot

17 March 2021: Over 50s start being offered Covid jabs in the UK

19 March 2021: Several European countries reverse decision to suspend AstraZeneca jab after initial investigations find no link to reported blood clots 

31 March 2021: People living with vulnerable adults are called forward to get a Covid vaccine in the UK, even if they are younger than eligible age groups

7 April 2021: UK restricts the use of the AstraZeneca vaccine to over-30s over a small but statistically significant risk of blood clots in younger people

30 April 2021: Over-40s are called forward for Covid jabs

7 May 2021: Restriction of the AstraZeneca vaccine is widened to include over-40s

August 2022: Government sources say they will not order anymore AstraZeneca Covid vaccines instead focuses on mRNA alternatives

March 2023: Dozens of patients and families launch legal action against AstraZeneca due to 

April 2023: Widower of a BBC presenter Lisa Shaw who died after having the vaccine said he has 'no alternative' but to sue AstraZeneca

4 August 2023: Anish Tailor, whose wife Alpa died in March 2021 after receiving her first AstraZeneca dose, filed a product liability claim against AstraZeneca at London's High Court. His lawyer says he has nearly 50 other clients who will formally sue AstraZeneca in the coming months

17 August 2023: IT engineer Jamie Scott, who suffered a brain haemorrhage the day after his first AstraZeneca jab starts a legal case against the company. The law firm representing Mr Scott says it represents around 40 other individuals or bereaved families 

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'Our efforts have been recognised by governments around the world and are widely regarded as being a critical component of ending the global pandemic.

'As multiple, variant Covid vaccines have since been developed, there is a surplus of available updated vaccines. 

'This has led to a decline in demand for Vaxzevria, which is no longer being manufactured or supplied. 

'AstraZeneca has therefore taken the decision to initiate withdrawal of the marketing authorisations for Vaxzevria within Europe.'

What did the original trial data show about side effects?  

Tens of thousands of volunteers, including ones in the UK and the US, willingly rolled up their sleeves to take part in original trials.

Heavily scrutinised data suggested two doses of the AstraZeneca jab offered about 70 per cent protection against becoming ill. This meant developing any symptoms, as opposed to being hospitalised.

Other studies calculated that a single dose reduced the likelihood of hospitalisation by up to 94 per cent.

Analysis of the phase 3 trial, the final hurdle typically needed to be cleared before any drug gets approved for widespread human use, noted no safety concerns.

Yet, like with all forms of medication, AstraZeneca's jab carried a range of potential side effects.

Officials knew about mild ones thanks to the massive trials, with recipients mostly complaining of routine issues like headaches.

And people who were subsequently vaccinated were warned about them ahead of getting any needle in their arm. 

Common side effects, which health bosses say can affect more than 10 per cent of recipients, include fatigue, 'flu-like' symptoms, and pain in the arms or legs. 

Stomach pain, a rash and excessive sweating were uncommon, strikes roughly one in 100 people who get vaccinated.

According to the pharmaceutical titan, rare (approximately one in 1,000) issues included facial drooping on one side. 

It was only once the door was opened for millions more Brits to get the jab, as the UK did during the first few months of 2021, that another complication was spotted.

Officials noted a small, yet significant trend in cases of vaccine-induced immune thrombotic thrombocytopenia (VITT, or TTS) that allowed them to raise the alarm in the first week of April. 

It causes blood clots to form in various parts of the body, including the brain, heart, lungs, kidneys, and the legs. It is an urgent medical emergency. 

These blood clots, like any others, can be deadly depending on where they form or if they break up and travel to parts of the body like the brain.

Estimates suggest the risk of blood clots occurring from taking AstraZeneca's jab is in the region of one in 50,000.

Am I at risk now if I had the jab back in 2021? 

Side effects from the AstraZeneca vaccine generally only occurred within the first four weeks of receiving it.

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