The Big Bang Theory promises exciting ends and new beginnings in hour-long ...

It's one of the most successful series on TV right now.

But fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday.

The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks.

End of an era: Fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday

End of an era: Fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday

Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project.

Then in The Stockholm Syndrome, the gang wraps things up as 'Bernadette and Wolowitz (Melissa Rauch and Simon Helberg) leave their kids for the first time.'

Meanwhile 'Penny (Kaley Cuoco) and Leonard (Johnny Galecki) try to keep a secret, Sheldon and Amy stick together and Koothrappali (Kunal Nayyar) makes a new friend, as the gang travels together into an uncharted future.'

The Big Bang Theory had been a hit since it first came onto the airwaves in 2007, earning blockbuster ratings, seven Emmy awards, and its own spin-off, Young Sheldon.

Laughs: The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks

Laughs: The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks

Suspense: Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project

Suspense: Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project

Talent: Above actors Kunal Nayyar, Simon Helberg, Joshua Malina and Johnny Galecki are seen from left to right

Talent: Above actors Kunal Nayyar, Simon Helberg, Joshua Malina and Johnny Galecki are seen from left to right

Parental supervision: In The Stockholm Syndrome, the gang wraps things up as 'Bernadette and Wolowitz (Melissa Rauch and Simon Helberg) leave their kids for the first time'

Parental supervision: In The Stockholm Syndrome, the gang

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