He's the host for Little Mix: The Search, which sees Jesy Nelson, Perrie Edwards, Leigh-Anne Pinnock and Jade Thirlwall find the next big group.
And Chris Ramsey was full of praise for the quartet and how they treat the show contestants, who are competing to win to perform in the supporting slot at the groups next big tour.
Detailing the show's safety precautions, after positive COVID-19 cases on set, the comedian, 34, said: 'As far I know is its okay, all I do is someone does a COVID test on me and I travel down to London if I’m all clear.
Gushing: Chris Ramsey detailed COVID-19 safety regulations on Little Mix: The Search as he praised the stars for being 'so caring' to contestants on Tuesday
'Either there’s four members of Little Mix or one on the telly, we'll see,' he joked, in reference to Jade Thirlwall who had to miss the programme's first live show as she was in self-isolation.
Chris then said of the quartet: 'The girls have been through this, not only they're such down to earth girls, they're so lovely, they've been through this process and are so caring with the guys who auditioned.
'We had six last week, and now down to 5, these six could all go on a talent show, I wouldn't want to bet on who would win they're all great.'
While he said of the top prize: 'It's probably the most tangible prize in any of these shows, you get to do the Royal Variety show with BGT, or get a record deal with X Factor and you don't know how that will pan out, but here you'll be on tour with one of the biggest girl groups in the world.'
Great judges: Chris said of the quartet: 'The girls have been through this, not only they're such down to earth girls, they're so lovely'
Safety first: Detailing the show's safety precautions, he added: 'As far I know is its okay, all I do is someone does a COVID test on me and I travel down to London if I’m all clear'
Lorraine Kelly joked