Kirstie Alley's best moments: Watch the tragic star in some of her most iconic ... trends now
She's had a Hollywood film and TV career spanning more than four decades.
And MailOnline has taken a look at some of Kirstie Alley's most iconic onscreen moments after it emerged on Monday that she has died from cancer aged 71.
Back in 1979, Kirstie appeared as a contestant on the game show Match Game. She won both rounds, winning $500 in the first round and $5500 in the second round.
Her final TV appearance was on The Masked Singer in April, which saw the acclaimed actress at her most playful and carefree.
Kirstie suited up as the fuzzy Baby Mammoth for the Fox singing competition, which took place just over seven months before her shocking death, and appears to have to have happened before she was diagnosed with cancer.
The former Cheers star and Golden Globe winner made her debut on season seven of the Fox series and performed Walkin' After Midnight by Patsy Cline.
But there have been plenty of roles in-between for this much loved actress, including a very sexy swimsuit-clad appearance in Prince Of Bel-Air in 1986.
She famously starred as Rebecca Howe in the NBC sitcom Cheers, alongside Ten Danson and Kelsey Grammer, for which she received an Emmy Award and a Golden Globe in 1991.
Kirstie also starred as the lead in the sitcom Veronica's Closet, earning yet more Emmy and Golden Globe nominations, for her role as the head of a NY lingerie company.
In 2011, she started appearing on reality TV, including Dancing With The Stars and moving onto UK Celebrity Big Brother, which she came in second place to British actor Ryan Thomas.
The actress leaves behind an incredible legacy, forging her career throughout the film and TV industry after growing up in Wichita, Kansas, and originally wanting to become an interior designer.
She also made headlines later in life, claiming last year that she had become 'blackballed' by Hollywood after vocally supporting Donald Trump.
Alley was born to the owner of a lumber company and a homemaker, leaving the Midwest for Los Angeles to pursue a career in interior design and also to explore Scientology.
Mourning: The Hollywood community is in mourning on Monday, with news that beloved actress Kirstie (seen above in a 2019 episode of Fox's Scream Queens) has passed away at 71 years of age, following a cancer battle
Legacy: The actress (seen in a portrait for Cheers) leaves behind an incredible legacy, forging her career throughout the film and TV industry after growing up in Wichita, Kansas, and originally wanting to become an interior designer
Blackballed: The actress (seen above in her 1982 film Star Trek II - The Wrath of Khan) also made headlines later in life, claiming last year that she had become 'blackballed' by Hollywood after vocally supporting Donald Trump
Early: Alley (seen above in a Profoundly Normal still) was born to the owner of a lumber company and a homemaker, leaving the Midwest for Los Angeles to pursue a career in interior design and also to explore Scientology
Alley landed her first major movie role in 1982, playing Vulcan Starfleet officer Saavik in Star Trek II: Wrath of Khan, which was the eighth-highest-grossing movie that year.
She was offered to return for the next two sequels, though she reportedly turned them down, claiming Paramount offered her less for the sequels than she was paid for Wrath of Khan.
The actress continued to work regularly on both the small and big screen, guest-starring in a 1983 episode of The Love Boat alongside her husband Parker Stevenson, and a slew of movies in 1984 including Runaway with Tom Selleck and Blind Date.
Major role: Alley (above left with William Shatner) landed her first major movie role in 1982, playing Vulcan Starfleet officer Saavik in Star Trek II: Wrath of Khan, which was the eighth-highest-grossing movie that year
Sequels: She was offered to return for the next two sequels, though she reportedly turned them down, claiming Paramount offered her less for the sequels than she was paid for Wrath of Khan
Continued: The actress continued to work regularly on both the small and big screen, guest-starring in a 1983 episode of The Love Boat alongside her husband Parker Stevenson (left in a photo circa 1983), and a slew of movies in 1984 including Runaway with Tom Selleck and Blind Date
She also got her first taste of a starring TV role with the 1983-1984 series Masquerade, for legendary TV writer Glen A. Larson, starring alongside Greg Evigan and Rod Taylor, though it only lasted one season.
Alley went on to play noted feminist Gloria Steinem in the 1985 TV movie A Bunny's Tale, chronicling Steinem's undercover investigation of Playboy clubs.
1987 would ultimately be a breakthrough year for Alley, when she landed the coveted role of Rebecca Howe on the hit series Cheers, taking over for the departing Shelley Long.
Taking over: 1987 would ultimately be a breakthrough year for Alley, when she landed the coveted role of Rebecca Howe on the hit series Cheers, taking over for the departing Shelley Long
She earned five Emmy nominations for her portrayal of Rebecca Howe on Cheers, winning her first Emmy in 1991, and her second in 1994 for the mini-series David's Mother.
She also starred in the hit 1987 movie Look Who's Talking alongside John Travolta, which was the 5th highest grossing movie of the year.
She went on to star in the 1990 film Madhouse with John Larroquette and returned as Mollie for Look Who's Talking Too that same year.
Emmy win: She earned five Emmy nominations for her portrayal of Rebecca Howe on Cheers, winning her first Emmy in 1991, winning her second in 1994 (above)
Talking: She also starred in the hit 1987 movie Look Who's Talking (above) alongside John Travolta, which was the 5th highest grossing movie of the year
Madhouse: She went on to star in the 1990 film Madhouse (above) with John Larroquette and returned as Mollie for Look Who's Talking Too that same year
She returned as Mollie once again for the 1993 sequel Look Who's Talking Now, the same year that Cheers ended it's iconic 11-season run.
Alley starred alongside Steve Guttenberg and