Common class of medications 'could increase dementia risk by almost half'

A common type of prescription medicine has been linked to an almost 50 per cent higher chance of getting dementia.

Anticholinergic drugs, which are used to treat people with epilepsy, Parkinson's, depression and incontinence, may be linked to the brain disorder.

Researchers studied more than 280,000 people in the UK to work out how the medicines affected someone's risk of dementia.

They found it was more common among people who were prescribed these types of drugs and suggested damage they cause to nerve cells could be to blame.

Although they said anticholinergic meds should be prescribed 'with caution' to older people, they also warned people not to stop taking their medication.

But if the link was found to be a direct cause the pills could be responsible for as many as one in 10 dementia cases, the experts added. 

The Nottingham researchers said people taking anticholinergic drugs may be at a 49 per cent higher risk of developing dementia, and that the commonly prescribed pills could even account for as many as one in 10 cases of the brain-destroying disease (stock image)

The Nottingham researchers said people taking anticholinergic drugs may be at a 49 per cent higher risk of developing dementia, and that the commonly prescribed pills could even account for as many as one in 10 cases of the brain-destroying disease (stock image)

Scientists at the University of Nottingham looked at decades' worth of prescribing and diagnosis data for 284,343 over-55s registered with GPs in the UK.

Nearly 59,000 of the people studied were diagnosed with dementia at some point.

Within the 11 years leading up to their dementia diagnosis, 56.6 per cent of the patients (33,253) had been prescribed anticholinergic medications.

The researchers said the odds of someone developing dementia increased by 49 per cent if they were given the drugs within 11 years of their diagnosis.

The biggest increases were seen in those who took antidepressants, anti-Parkinson's drugs, antipsychotics, antiepileptic drugs and those used to control bladder incontinence.

Professor Tom Dening said: 'This study provides further evidence that doctors should be careful when prescribing certain drugs that have anticholinergic properties.

'However, it's important that patients taking medications of this kind don't just stop them abruptly as this may be much more harmful.

'If patients have concerns, then they should discuss them with their doctor to consider the pros and cons of the treatment they are receiving.'

Professor Dening and his colleagues made it clear that their paper only pointed to a link between the prescriptions and the rate of dementia.

WHAT IS DEMENTIA? 

Dementia is an umbrella term used to describe a range of progressive neurological disorders, that is, conditions affecting the brain.

There are many different types of dementia, of which Alzheimer’s disease is the most common.

Some people may have a combination of types of dementia.

Regardless of which type is

read more from dailymail.....

NEXT No wonder you can't get an NHS dentist appointment! Outrage as taxpayer-funded ... trends now