Covid variant XBB.1.5 already makes up HALF of cases in worst-hit places...has ... trends now

Covid variant XBB.1.5 already makes up HALF of cases in worst-hit places...has ... trends now
Covid variant XBB.1.5 already makes up HALF of cases in worst-hit places...has ... trends now

Covid variant XBB.1.5 already makes up HALF of cases in worst-hit places...has ... trends now

A new Omicron subvariant that is starting to sweep the UK is behind up to half of all Covid cases in the worst-hit regions, surveillance data suggests.

Figures from the Sanger Institute, one of the UK's largest Covid surveillance centres, shows 50 per cent of cases in Wirral last week were caused by XBB.1.5, nicknamed the Kraken.

The strain has caused a surge of cases in the US, with some experts concerned that its mutations could see it trigger a similar spike in the UK by dodging the wall of immunity built up from previous waves and vaccine roll-outs.

It comes as UK ministers rush to bring in testing rules ahead of an expected influx of travellers from China, which is being crippled by its biggest surge since the pandemic began, with hospitals and crematoriums filling up.

Figures from the Sanger Institute, one of the UK's largest Covid surveillance centres, show XBB.1.5 was spotted nine times in the week to December 17. Five of the cases were spotted in Wirral in Merseyside, where scientists estimate it is behind 50 per cent of cases. One XBB.1.5 sample was sequenced in Stroke-on-Trent, where 20 per cent of cases are thought to be caused by the strain. Telford and Wrekin in Shropshire (11 per cent), Tower Hamlets in London (50 per cent) and Cornwall (33 per cent) all each reported one strain caused by the Omicron sub-variant

Figures from the Sanger Institute, one of the UK's largest Covid surveillance centres, show XBB.1.5 was spotted nine times in the week to December 17. Five of the cases were spotted in Wirral in Merseyside, where scientists estimate it is behind 50 per cent of cases. One XBB.1.5 sample was sequenced in Stroke-on-Trent, where 20 per cent of cases are thought to be caused by the strain. Telford and Wrekin in Shropshire (11 per cent), Tower Hamlets in London (50 per cent) and Cornwall (33 per cent) all each reported one strain caused by the Omicron sub-variant

Figures from the Sanger Institute, one of the UK's largest Covid surveillance centres, shows 4 per cent of cases in the week to December 17 were caused by XBB.1.5 (shown in purple, bottom right corner)

Figures from the Sanger Institute, one of the UK's largest Covid surveillance centres, shows 4 per cent of cases in the week to December 17 were caused by XBB.1.5 (shown in purple, bottom right corner)

December 17 marked the first time XBB.1.5 was listed on the institute's virus dashboard, which is updated weekly

December 17 marked the first time XBB.1.5 was listed on the institute's virus dashboard, which is updated weekly

NHS hospitals have been ordered to sequence positive swabs from infected travellers from China over concerns a mutant variant will emerge 

The UK Health Security Agency is stepping-up its Covid sequencing for hospitalised patients who have travelled to Britain from China over concerns a mutant variant will emerge. 

China is battling is biggest outbreak since the pandemic began, with some estimates suggesting that it is experiencing one million cases and 5,000 deaths per day, with hospitals and crematoriums overwhelmed. 

The nation has stopped sharing data on daily Covid cases and deaths and is only sharing a low level of sequencing data.

While travel from China to the UK is 'currently low' it is 'likely to increase' next week in response to Beijing lifting quarantine requirements for returning travellers, the UKHSA said.

Available genome data from China and other countries testing arrivals from the nation suggests Omicron sub-variants — including those already circulating in Europe — are spreading.

But leaders remain concerned that a new variant will emerge from the surge in cases that evades the immune response — which could 'pose a threat'.

In a bid to stay ahead of worrying strains, the UKHSA has told hospitals to inform it of any Covid patients who have been to China in the previous two weeks, conduct a PCR test and alert laboratories to the case.

In a letter, sent by UKHSA chief medical advisor Professor Susan Hopkins, the agency's deputy chief medical officer Dr Thomas Waite and NHS England medical director Professor Stephen Power, labs were told to send any swabs from travellers from China to the UKHSA for 'expedited sequencing'.

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Sanger Institute data, based on hundreds of samples, shows 4.3 per cent of cases in the week to December 17 were caused by XBB.1.5.

It is the first time the strain has been listed on the institute's virus dashboard, which is updated weekly. 

Overall, the strain was spotted nine times that week.

Five of the cases were spotted in Wirral in Merseyside, where scientists estimate it is behind 50 per cent of cases.

One XBB.1.5 sample was sequenced in Stroke-on-Trent, where 20 per cent of cases are thought to be caused by the strain.

Telford and Wrekin in Shropshire (11 per cent), Tower Hamlets in London (50 per cent) and Cornwall (33 per cent) all each reported one case caused by the Omicron sub-variant.

The Sanger Institute notes that the number of samples it sequences has reduced since April 1 2022 — when free tests were scrapped in England. 

And its data does not include all Covid swabs which are sequenced across the UK, meaning there may be extra cases not included in its figures. 

Some scientists are concerned about XBB.1.5 due to its mutations, including F486P, which helps it to bypass Covid-fighting antibodies that were generated in response to vaccination or previous infection.

Another change — S486P — is thought to improve its ability to bind to cells. 

The strain, which is thought to have emerged in the US, is a mutated version of Omicron XBB, which was first detected in India in August. 

XBB, which is a merger of variants BA.2.10.1 and BA.2.75, caused cases to quadruple in just one month in some nations. 

Real-world data also shows how the strain is currently sweeping the US.

Data from the US Centers for Disease Control and Prevention (CDC) on Friday showed that the strain is behind 41 per cent of

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