Brain stimulation successfully treats depression in mice

Scientists at the Children's Hospital of Philadelphia found that a pathway linked to memory is also linked to mood By stimulating proteins in that pathway they triggered 'antidepressive behavior' in mice The researchers say this could pave the way to drug-free alternatives

By Mia De Graaf Health Editor For Dailymail.com

Published: 16:37 BST, 16 April 2018 | Updated: 16:41 BST, 16 April 2018

View
comments

Scientists have successfully treated depression in mice using brain stimulation - paving the way to a drug-free alternative for mental health care. 

Tens of millions of Americans are hooked on highly-addictive and costly medication that relieves their anxiety and depression but triggers debilitating withdrawal symptoms if they try to come off. 

As the rate of depression soars in America, scientists are scrambling to identify alternative treatments for patients. 

Now, a team at the Children's Hospital of Philadelphia (CHOP) has shown that a pathway in brain circuitry can be stimulated to create 'antidepressive' behavior in animals.

A team at the Children's Hospital of Philadelphia has shown a brain pathway can be stimulated to create 'antidepressive' behavior in mice, sparking hope for drug-free treatment in humans

A team at the Children's Hospital of Philadelphia has shown a brain pathway can be stimulated to create 'antidepressive' behavior in mice, sparking hope for drug-free treatment in humans

The study, published today in Nature Medicine, has been hailed as a potential breakthrough in mental health care.

'Major depressive disorder is a serious health problem worldwide. Existing treatments are helpful for many people, but also have a high rate of relapse and significant side effects,' said study leader Dr Amelia J Eisch, a neurobiology researcher at Children's Hospital of Philadelphia (CHOP).

'Because scientists consider depression to be caused by malfunctions in brain circuitry, we suggest that "tuning" a

read more from dailymail.....

Get the latest news delivered to your inbox

Follow us on social media networks

NEXT Marathon champion Ron Hill on the dementia that means he can recall his races ...