England take on Ireland in Dublin on Saturday afternoon in a heavyweight start to both sides' Six Nations campaigns'.
Eddie Jones' England side make the trip to determined to lay down a marker after losing both their world No 2 ranking and Six Nations crown to Joe Schmidt's side in 2018.
Sportsmail's NIK SIMON runs the rule over the two teams before their crunch meeting at the Aviva Stadium.
Defending Six Nations champions Ireland face Eddie Jones' England on Saturday afternoon
Robbie Henshaw - Full-back
Age: 25 Caps: 37
Family history in Gaelic football should help the centre shift to his new position. 6.5.
Keith Earls - Wing
Age: 31 Caps: 72
Puts good form partly down to work with hypnotist and magician Keith Barry. 7.5.
Ireland winger Keith Earls put his good form partly down to the work of hypnotist Keith Barry
Garry Ringrose - Centre
Age: 24 Caps: 17
Burdened by Brian O'Driscoll comparisons but classy blend of skill and speed. 8.
Bundee Aki - Centre
Age: 28 Caps: 12
Power match-up with Tuilagi - 12 years after they faced off as schoolboys. 7.5.
Jacob Stockdale - Wing
Age: 22 Caps: 14
Last year's top scorer clocked speeds of 10.1 metres per second in his last outing. 8.5
Johnny Sexton - Fly-half
Age: 33 Caps: 79
Eddie Jones claims the world player of the year has a 'batphone' to the ref. 9.
Eddie Jones will be well aware of the real danger posed by Ireland's star man Johnny Sexton
Conor Murphy - Scrum-half
Age: 29 Caps: 68
Lions star will test England's back three with his pinpoint box-kicking. 8.5.
Cian Healy - Prop
Age: 31 Caps: 84
Decade of Test experience could help him get under Sinckler's skin. 7.
Rory Best - Hooker
Age: 36 Caps: 114
The question is: does the nuggety hooker still have the engine at 36? 7.
Tadhg Furlong - Prop
Age: 26 Caps: 28
The world's complete prop because of his size and slick ball-handling skills. 9.
Tadhg Furlong (centre) is the world's most complete prop due to his size and handling skills
Devin Toner - Second row
Age: 32 Caps: 64
His 6ft 10in frame means George's lineout's must be pinpoint accurate. 7.
James Ryan - Second row
Age: 22 Caps: 13
Tipped as future Lions captain. Dominant tackling and gainline breaking. 8.5.
Peter O'Mahony - Blindside
Age: 29 Caps: 53
Emotional leader of the team with gritty and abrasive edge in close quarters. 8.