Perhaps Claudio Ranieri realised his reign at Fulham was ill-fated the moment £20million central defender Alfie Mawson injured himself just by putting his boots on.
Maybe it was the sight of striker Aboubakar Kamara and Aleksandar Mitrovic fighting during a yoga session. Or Kamara then being arrested at their west London training ground two weeks later on suspicion of criminal damage and actual bodily harm against a security guard.
Perhaps it could have been when the team-bonding go-karting trip he authorised was cancelled because the club decided the insurance costs were too high.
Or the carefree looks on his players' faces when they flew to Amsterdam for a Christmas party immediately after losing 4-1 to Manchester United at Old Trafford. Take your pick.
His last match was a 2-0 defeat by Southampton at St Mary's Stadium on Wednesday
You could even say the equaliser they conceded against West Ham last week. Javier Hernandez bundled the ball over the line using his left hand and fragile Fulham went on to lose 3-1 at the London Stadium, which just about sums up their rotten luck.
It has been one thing after another. Ranieri was described as 'risk-free' by owner Shahid Khan following his arrival in November, but he has been unable to tinker them out of trouble.
Wednesday evening's 2-0 defeat at Southampton was the final straw for vice-chairman Tony Khan, who had spent this week at the training ground overseeing the current set-up.
It was Fulham's biggest fixture of the season so far — a must-win for both sides — but Ranieri raised eyebrows at a team meeting before their trip to St Mary's Stadium.
The 'Tinkerman' told his players that, for the first time, they would be playing a 4-1-2-1-2 formation. It meant defensive