By Nik Simon for the Daily Mail
Published: 22:43 GMT, 8 March 2019 | Updated: 23:41 GMT, 8 March 2019
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Eddie Jones has rung the changes for England against Italy, with five players coming into the team that lost to Wales at the Principality Stadium.
Sportsmail's NIK SIMON takes at look at which players can make a difference in England's penultimate Six Nations clash.
England will be looking to bounce back against Italy after defeat by Wales in their last game
ELLIOT DALY
AGE: 26 CAPS: 28
Likely to step in as a second playmaker in a backline dominated by heavyweights.
JOE COKANASIGA
AGE: 21 CAPS: 3
Tips the scales at 18st 3lb and clocks speeds of 10metres per second over 50m.
Joe Cokanasiga is granted his Six Nations debut and is a powerful and direct runner
MANU TUILAGI
AGE: 27 CAPS: 30
Eddie Jones compares centre pairing to Bok heavies Francois Steyn and Jaque Fourie.
BEN TE'O
AGE: 32 CAPS: 16
Questions over fitness as league convert makes his first appearance since January.
Worcester centre Ben Te'o has returned after seven weeks out injured and will start
JONNY MAY
AGE: 28 CAPS: 43
