While Jose Mourinho, Jurgen Klopp, Pep Guardiola and the rest of the Premier League's managers will be glad to see the back of this international break, business is still to be settled with the Nations League reaching its conclusion.
France secured their spot in the Finals by beating defending champions Portugal courtesy of an N'Golo Kante goal but aside from Didier Deschamps' men, there are plenty of spots still up for grabs.
There's also the dreaded relegation that faces a number of teams and so Sportsmail has broken down the 14 groups to work out what's still to play for and who to keep an eye on...
Gareth Bale and Wales are on course for promotion to League A if they avoid defeat to Finland
Germany face a straight shoot-out against Spain for a spot in the Nations League Finals
What can still happen?
In short: lots.
Only France - in Group A3 - have secured passage through to the Nations League Finals and so the final round of games arrives finely poised.
Take Group A1 as an example: Italy, Holland, Poland and Bosnia and Herzegovina.
Bosnia have been unsurprisingly relegated in such a tricky group but heading into the final matchday, each of the other three hold legitimate opportunities to reach the Finals.
Roberto Mancini's Italy know they will reach the finals if they beat Bosnia and Herzegovina. Failing that they could make it through if they draw and the Holland do not beat Poland. Failing that, a draw in the other game would see them through.
Georginio Wijnaldum has impressed for Holland but they are relying on a favour from Bosnia
So, truth be told, Italy are in control here. But Holland will reach the finals if they beat Poland and Italy do not beat Bosnia. For Poland they need to beat Holland and get a favour from Bosnia in Sarajevo.
There is less tension and drama in England's group - Group A2 - after Gareth Southgate's side were well beaten by Belgium. Now a dead rubber against an already relegated Iceland awaits.
Belgium are in control and will reach the Finals if they avoid defeat against Denmark, the other side who can make the last stage of the tournament.
A winner takes all scenario at the King Power Stadion At Den Dreef on Wednesday.
Cristiano Ronaldo and his Portuguese team-mates were left exasperated at having lost to France on Saturday, robbing them a chance to defend their title having secured the runners-up spot in Group A3.
This quartet is all about relegation - 2018 World Cup finalists Croatia, who host Portugal in Split, will avoid the drop if they manage to pick up more points than Sweden.
Both sit on three points apiece currently and if they remain level on points, relegation will be determined by overall goal difference - currently level on minus-six - then goals scored, which favours Croatia by four.
Jack Grealish and England have nothing left to play for having been beaten by Belgium
Then comes Group A4, arguably the pièce de résistance of this latest Nations League campaign.
Nothing settled. All to play for. Two sides fighting for a Finals spot. Two sides head-to-head to avoid relegation. It is set up perfectly.
Germany, who lead the group by a single point, after a Timo Werner-inspired 3-1 win against Ukraine on Saturday, will progress if they can just avoid defeat against Spain.
Luis Enrique's side looked out of sorts against Switzerland but have genuine world class stars in their ranks. They know victory over Germany will make up for the hiccups to date.
On the flip side comes the dreaded relegation for two sides who expected to be in this position when the make-up of the groups became clear.
Ukraine will be relegated if they lose to Switzerland 1-0, 2-1 or by a margin of two goals or more.
Switzerland need to win by the same margins or their days in League A, for now at least, would be over.
Luis Enrique knows if Spain overcome Germany then his side will book a spot in the Finals
Who to keep an eye on?
The top tier, the stars on show, there is no shortage of ones to watch.
Germany is full of Premier League talent with Chelsea fans no doubt strapping themselves in to see what could well be another Werner masterclass.
The emerging superstar in Germany's ranks is Serge Gnabry and starting at centre forward against Ukraine, the Bayern Munich attacker once again looked a cut above.
Then there's Spain, the side in Germany's way for a spot in the Finals.
Enrique's side have had trouble scoring goals - something he insisted is NOT a problem - but he needs big performances from Mikel Oyarzabal and Ferran Torres on the wings if he is to go toe to toe with Germany's fearsome attack.LEAGUE B
What can still happen?
A group thrown into chaos because of coronavirus, two home nations chasing promotion and a very complicated three-way fight between Russia, Hungary and Turkey for top spot.
While there are no prizes to reach the Finals here like there is in League A, there is the carrot dangling of a place in the top leagues next time round.
Let's start with Group B1, a group in disarray due to a coronavirus outbreak in the Norwegian national team.
Norway, who sit second, were blocked from travelling to Romania for the final game and so the fixture, naturally, cannot go ahead.
'The matter will now be submitted to the UEFA Control, Ethics and Disciplinary Body, for a decision to be taken in accordance with the special rules applicable to UEFA National Team competition matches, as approved by the UEFA Executive Committee on 29 August 2020,' a statement read.
Erling Haaland is not to be involved as Norway fight to save their Nations League campaign