The Cleveland Browns (3-3) and the Denver Broncos (3-3) will face off on Thursday Night Football. Both teams are currently on losing streaks -- Cleveland at two games, and Denver at three -- and will hope to get back on track. The Browns have been hit with the injury bug and will be without several major contributors. Running backs Nick Chubb and Kareem Hunt will both miss this game with calf injuries, while quarterback Baker Mayfield, who aggravated his left shoulder injury in the loss to the Arizona Cardinals, is listed as questionable on the team's injury report.
Kickoff from FirstEnergy Stadium is set for 8:20 p.m. ET. Cleveland is favored by three points in the latest Broncos vs. Browns odds from Caesars Sportsbook, while the Over-Under is 42.5. Before locking in any Browns vs. Broncos picks, you need to check out the NFL predictions and analysis from the proven SportsLine Projection Model.
The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has simulated Browns vs. Broncos 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model's picks. Now, here are several NFL odds and betting lines for Browns vs. Broncos:
Broncos vs. Browns spread: Browns -3 Broncos vs. Browns over-under: 42.5 points Broncos vs. Browns money line: Cleveland -170, Denver +145 CLE: Browns are 7-3 ATS in their last 10 Thursday games DEN: Over is 4-1 in Broncos' last five games following a straight-up lossFeatured Game | Cleveland Browns vs. Denver Broncos
The Browns have been hit hard by the injury bug in 2021. Odell Beckham Jr., Nick Chubb, Jack Conklin, A.J. Green, Kareem Hunt, Baker Mayfield, Jeremiah Owusu-Koramoah, Malcolm Smith, JC Tretter, and Jedrick Wills all missed practice Monday, and several other key players were listed on the team's injury report.
If Mayfield is unable to go, the Browns will turn to veteran backup Case Keenum, who was Denver's starting quarterback in 2018. D'Ernest Johnson is expected to get the start at running back for Cleveland.
Defensively, the Browns are in better shape, but still have several players battling nagging injuries. With Denver's offensive line struggling, Garrett and fellow defensive end Jadeveon Clowney could have a field day.
Why the Broncos can coverThe Broncos average 368.3 total yards per game, which ranks 13th in the league. Denver has been able to mix in the run with the pass, averaging 250.8 passing yards with another 117.5 on the ground. This balance forces the defense to stay on their toes.
Quarterback Teddy Bridgewater has thrown for 300-plus yards in two games this season. Despite throwing three interceptions in last week's performance against the Las Vegas Raiders, Bridgewater still put up solid numbers, going 35-of-49 for 334 yards with three touchdowns. The Broncos' offense is versatile and has plenty of playmakers, including wide receiver Courtland Sutton and rookie running back Javonte Williams, around Bridgewater.
How to make Broncos vs. Browns picksSportsLine's model is leaning over on the point total, projecting the teams to combine for 44 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model's Broncos vs. Browns picks at SportsLine.
So who wins Browns vs. Broncos on
