NFL odds, Vegas lines, picks, spreads, bets, predictions for Week 7, 2021: Model loving Patriots, Lions

As is often the case, the Kansas City Chiefs are involved in a game with the highest Over-Under on the Week 7 NFL schedule. Patrick Mahomes will lead K.C. into Tennessee, with Chiefs vs. Titans getting an Over-Under of 57 in the latest NFL odds at Caesars Sportsbook. Only one other game on the schedule even eclipses 50 total points. The Chiefs are favored by 5.5 points in the latest Week 7 NFL spreads as they attempt to win back-to-back games for the first time this season.

Should you back Mahomes and the Chiefs in your Week 7 NFL predictions despite their up and down season? Can the Titans build off their impressive Monday Night Football victory over the Bills? Whether you're placing your Week 7 NFL bets on this game or others, it would be wise to have some assistance in making NFL predictions. All of the Week 7 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 7 NFL picks now. 

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 7 NFL odds from Caesars and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 7 NFL predictions

One of the model's strongest Week 7 NFL picks is that the Patriots (-7) cover the spread against the Jets in 60 percent of simulations. It's been a slog for Bill Belichick since Tom Brady left for the Buccaneers, with New England going 7-9 last season and off to a 2-4 start in 2021. However, the Patriots have taken two of the best teams in the NFL to the wire and also collected a needed win over the Texans in the last three weeks.

The Patriots hosted Brady in Week 4 and were an upright away from winning outright as 6.5-point underdogs. Then they took the Cowboys to overtime. Meanwhile, the Jets have given up 880 yards the last two weeks and haven't put up more than 355 yards of total offense in a game all season.

New England has covered the spread in seven of its last 10 against the Jets. Mac Jones is clearly the more developed of the two rookie quarterbacks at this point and the model predicts two more interceptions from Zach Wilson as the Patriots cover in nearly 60 percent of simulations.

Another one of the model's Week 7 NFL predictions: The Lions (+15) cover against the Rams well over 50 percent of the time. While the Lions are neither particularly explosive on offense nor stout on defense, they do excel in the field position game thanks to punter Jack Fox. The Pro Bowler's punting average of 51.5 yards would be the second-highest in NFL history if he maintains that number. His ability to force opposing offenses to go on long drives is a reason why the Rams aren't expected to light up the scoreboard for 38 points like they did last week.

Lions quarterback Jared Goff is projected to get some level of revenge on his former team by tossing a touchdown and passing for more than 230 yards. Meanwhile, the two-headed backfield of Jamaal Williams and D'Andre Swift will combine for 120 yards from scrimmage as factors on the ground and through the air. Those contributions are just enough to keep the Lions competitive, as the model has Detroit (+15) covering in over 50 percent of simulations.

How to make Week 7 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 7 NFL schedule, and it's calling for a Super Bowl contender to go down hard. You can only get every pick for every game at SportsLine.

So what NFL picks can you make with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $7,700 since its inception, and find out.

Week 7 NFL odds, spreads, lines

Sunday, Oct. 24

Bengals at Ravens (-6.5, 47)

Panthers at Giants (+3, 43)

Washington at Packers (-7.5, 49)

Chiefs at Titans (+5.5, 57.5)

Falcons at Dolphins (+2.5, 47.5)

Jets at Patriots (-7, 42.5)

Lions at Rams (-15, 50.5)

Eagles at Raiders (-3, 49.5)

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