Rams vs. Lions odds, line, spread: 2021 NFL picks, Week 7 predictions from proven computer model

Rams vs. Lions odds, line, spread: 2021 NFL picks, Week 7 predictions from proven computer model
Rams vs. Lions odds, line, spread: 2021 NFL picks, Week 7 predictions from proven computer model

The Los Angeles Rams will take on the Detroit Lions at 4:05 p.m. ET on Sunday at SoFi Stadium. Los Angeles is 5-1 overall and 2-1 at home, while Detroit is 0-6 overall and 0-3 on the road. The Rams beat the Giants last week, 38-11. Detroit lost to Cincinnati, 34-11.

The Rams have won two of the past three games between the teams. Los Angeles is favored by 16 points in the latest Rams vs. Lions odds from Caesars Sportsbook, and the over-under is set at 50.5. Before entering any Lions vs. Rams picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season. 

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Rams vs. Lions. You can head to SportsLine to see its picks. Here are several NFL betting lines for Lions vs. Rams:

Rams vs. Lions spread: Rams -16 Rams vs. Lions over-under: 50.5 points

Featured Game | Los Angeles Rams vs. Detroit Lions

What you need to know about the Rams

The Rams raced out to a 28-3 halftime lead in their win over the Giants last week. Matthew Stafford passed for four TDs with one interception for a 128.7 rating. Now he faces the Lions, who traded him to Los Angeles in the offseason. Stafford spent 12 seasons (2009-20) with Detroit and is the Lions' all-time leader in passing yards (45,109) and passing TDs (282). 

Cooper Kupp had nine catches for 130 yards and two TDs last week. He became just the second NFL player ever with 45-plus catches (46), 650-plus receiving yards (653) and seven TD receptions in his first six games of a season. Darrell Henderson had 107 scrimmage yards (78 rushing) and two TDs (one rushing, one receiving) in Week 6 and he has 80-plus scrimmage yards in his last five games. 

What you need to know about the Lions

Jared Goff, who was traded to Detroit by Los Angeles in the deal involving Stafford in the offseason, will now play against the Rams for the first time. He was selected first overall by the Rams in the 2016 NFL Draft. He had 18,171 pass yards and 117 TDs (107 passing) in 69 starts from 2016-20 and helped lead the team to Super Bowl LIII. Last week, Goff did not throw a TD pass and was intercepted once while passing for 202 yards vs. the Bengals

Detroit did not score in the first half for the third time in four weeks by the Bengals. The Lions have the NFL's longest active losing streak, at 10 games. D'Andre Swift

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