A pair of two-win teams will meet on Sunday Night Football as the San Francisco 49ers (2-3) host the Indianapolis Colts (2-4). While 49ers quarterback Jimmy Garoppolo has been dealing with a calf injury, Colts quarterback Carson Wentz has been on the best stretch of his career. He's thrown for six touchdowns and zero picks over his last three games, surely rewarding those who slotted him into their NFL DFS lineups.
Even with T.Y. Hilton in and out of the lineup, other Colts pass-catchers have stepped up over this stretch and helped out Wentz. Michael Pittman Jr. is on pace for over 1,100 receiving yards, while tight end Mo Allie-Cox has three scores over his last three games. Should either of those players factor into your NFL DFS strategy for Colts vs. 49ers? Before submitting your NFL DFS lineups for Sunday Night Football, be sure to check out the NFL DFS advice, player rankings, stacks and top daily Fantasy football picks from SportsLine's Mike McClure.
McClure is a legendary professional DFS player with almost $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments last season.
He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.
Now, McClure has turned his attention to Sunday Night Football slate and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.
Top NFL DFS picks for Colts vs. 49ersOne of McClure's top NFL DFS picks for Sunday Night Football is Wentz. The former Eagle didn't have to do much in last week's 31-3 beatdown of the Texans, but Wentz was efficient with two touchdown passes on just 11 pass completions. It was also the third straight game he posted a passer rating above 115.
Wentz should keep the hot streak going against a Niners defense that isn't as vaunted as years past. San Francisco has the second-fewest interceptions in the league, while Wentz has the fewest thrown INTs of any starting quarterback. Sometimes avoiding negative-point plays are as important as accumulating positive-point plays and Week 7 certainly favors Wentz. Thus, you can see why McClure is high on him for Sunday Night Football.
Part of McClure's optimal NFL DFS strategy also includes stacking Wentz with running back Jonathan Taylor, who is coming off his best game of the season with 145 rushing yards and two touchdowns in Week 6. Taylor did that on just 14 carries and the yardage total was the third-highest of his career.
After a slow start to the year, Taylor has been arguably the best back in the league not named Derrick Henry over the last three weeks. He's averaged 147 yards from scrimmage over this stretch with five touchdowns scored. He ranks second in the NFL in scrimmage yards (682) and has become a huge factor in the passing game as he's on pace to nearly double his receiving yardage from a year ago.
How to set NFL DFS lineups for 49ers vs. ColtsMcClure is also targeting an undervalued player who is set to explode for huge numbers on Sunday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.
So who is Mike
