The Minnesota Vikings will take on the San Francisco 49ers at 4:25 p.m. ET on Sunday at Levi's Stadium. San Francisco is 5-5 overall and 1-4 at home, while the Vikings are 5-5 overall and 2-3 on the road. The Niners have won three of their last four games. Minnesota has won two consecutive games.
The Vikings have won four of the past five games between the teams. San Francisco is favored by three points in the latest 49ers vs. Vikings odds from Caesars Sportsbook, and the over-under is set at 49. Before entering any Vikings vs. 49ers picks, you'll want to see the NFL predictions from the model at SportsLine.
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Featured Game | San Francisco 49ers vs. Minnesota Vikings
The 49ers routed the Jacksonville Jaguars last Sunday, 30-10 on the road. Deebo Samuel had 94 scrimmage yards (career-high 79 rushing) and his third rushing TD of the season. He became the first WR in the Super Bowl era with three-plus rushing TDs in two of his first three seasons. George Kittle caught a TD pass in his third consecutive game.
Nick Bosa had two sacks in Week 11 and has a career-high 10 sacks in 2021. Josh Norman leads the league with six forced fumbles. Elijah Mitchell (rib/finger) is listed as questionable for Sunday's game.What you need to know about the Vikings
Meanwhile, Minnesota edged the Green Bay Packers, 34-31. Greg Joseph made a 29-yard field goal as time expired. Kirk Cousins passed for 341 yards and three touchdowns. He has 25 games with 300-plus passing yards and three-plus TD passes, the second-most by an NFL QB in his first 10 seasons all-time.
Justin Jefferson had eight receptions for 169 yards and two TDs. He has 11 games with 100-plus receiving yards, tied for the second-most by a WR in his first two