2022 NFL playoff odds, picks, line, spread: Packers vs. 49ers predictions, best bets from expert who's 50-16

2022 NFL playoff odds, picks, line, spread: Packers vs. 49ers predictions, best bets from expert who's 50-16
2022 NFL playoff odds, picks, line, spread: Packers vs. 49ers predictions, best bets from expert who's 50-16

Eight teams remain in the 2022 NFL playoffs, with two squads facing off in primetime on Saturday. Lambeau Field hosts a matchup between the Green Bay Packers and San Francisco 49ers, with the 49ers trying to pull off a second straight upset. The 49ers entered the postseason as the No. 6 seed in the NFL playoff bracket before toppling the Dallas Cowboys a week ago. The Packers enjoyed a bye week as the No. 1 seed, and Green Bay posted a 13-4 record during the regular season.

Kickoff is at 8:15 p.m. ET in Green Bay. Caesars Sportsbook lists the Packers as 5.5-point home favorites, while the Over-Under, or total number of points Vegas thinks will be scored, is 47 in the latest Packers vs. 49ers odds. Before you make any 49ers vs. Packers picks and NFL playoff predictions, make sure you check out what SportsLine NFL expert R.J. White has to say.

CBS Sports' Fantasy and gambling editor, White ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest.

In addition, White has gone an astounding 50-16-1 on his last 67 picks involving Green Bay, returning more than $3,100. Anyone who has followed him is way up.

Now, White has set his sights on 49ers vs. Packers, and just locked in his coveted picks and NFL playoff predictions. You can head to SportsLine to see White's picks. Now, here are several NFL playoff odds and divisional round betting lines for 49ers vs. Packers:

Packers vs. 49ers spread: Packers -5.5 Packers vs. 49ers over-under: 47 points  Packers vs. 49ers money line: Packers -240, 49ers +200  SF: 49ers are 5-1 against the spread in their last six games  GB: Packers are 12-5 against the spread this season

Featured Game | Green Bay Packers vs. San Francisco 49ers

Why the 49ers can cover

San Francisco has notable strengths on both offense and defense. The 49ers are scoring 25.1 points per game while allowing only 21.5. San Francisco is in the top eight in total offense, generating more than 375 yards per game, and No. 3 in total defense, giving up 310. Kyle Shanahan's team is No. 2 in yards per pass attempt (8.6) with only 33 sacks allowed and top-tier marks in completion rate (66.7 percent) and passer rating (127.4).

The 49ers also average 127.4 rushing yards per game, and the Packers are giving up 4.7 yards per carry on defense, No. 30 in the NFL. San Francisco ranks in the top seven in rushing defense, passing defense and fumbles recovered, with the 49ers allowing only 26 passing touchdowns.

Why the Packers can cover

The Packers threw for more than 4,300 yards in 17 games this season and generated 39 passing touchdowns during the regular season. No team tossed fewer interceptions (seven) or committed fewer turnovers (13) than the Packers, who completed nearly 68 percent of their passes.

The Packers also averaged 7.6 yard per pass attempt, allowing only 33 sacks this season. Green Bay finished in the top 10 in both third down efficiency (43.6 percent) and fourth down efficiency (59.1 percent), making it difficult for opponents to close drives. In fact, the Packers scored on 44.5 percent of possessions, averaging 2.54 points per drive and 35.9 yards per drive, both of which rank in the top five.

How to make 49ers vs. Packers picks

White has analyzed this matchup and while we can tell you he's leaning under on the point total, he has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side of the Packers vs. 49ers spread to back, at SportsLine.

So who wins 49ers vs. Packers in the NFL

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