The Grand National returns with Minella Times vying to repeat the feat of Tiger Roll and win the race for a second year running.
The likes of Snow Leopardess and Delta Work are favoured to spoil the Blackmore party.
Forty runners will compete in the four-and-a-quarter mile handicap chase to cement their place in British horse racing folklore.
Sportsmail runs you through all of the runners and riders and their chances in the world's most famous race.
Rachael Blackmore is out to achieve the rare feat of consecutive Grand National victories
1 Minella Times, Rachael Blackmore: Last year’s winner returns to defend his crown but two starts this term have been less than inspiring. Has plenty more on his plate this time off revised mark. ✶✶ 10-1
2 Delta Work, Jack Kennedy: Multiple Grade One winner who reignited career by ruining Tiger Roll’s swansong at Cheltenham. Not always the cleanest jumper so needs to bring A game here. ✶✶✶✶ 9-1
3 School Boy Hours, Sean Flanagan: Failed Cheltenham Festival exam but was still in touch when stumbling. Interesting contender on evidence of Leopardstown Festival win. ✶ 20-1
4 Any Second Now, Mark Walsh: Unfortunate last year when hampered at a crucial stage and this year’s preparation has gone swimmingly. Looks to be peaking at the right time. ✶✶✶✶ 8-1
Snow Leopardess is fancied by the bookies and will begin the race as favourite
5 Run Wild Fred, Davy Russell: Boasts plenty of form in staying handicaps with big fields so may find this more suitable than latest Cheltenham test. Races handily and jumps well. Each-way appeal. ✶✶✶✶ 14-1
6 Lostintranslation, Harry Cobden: Finished third in the Gold Cup two years ago but found success harder to come by since. Suited by a flat track and may outrun his odds if taking to this test. ✶✶ 50-1
7 Brahma Bull, Brian Hayes: Following an encouraging start to the season, jumping has not been his strong point of late and two non-completions leave him facing a huge task. ✶ 66-1
8 Burrows Saint, Paul Townend: Winner of the 2019 Irish National looked to be delivering a huge challenge in last year’s renewal until the petrol ran out late on. Still boasts an each-way shout. ✶✶✶ 22-1
9 Mount Ida, Denis O'Reagan: JOCKEY: DENIS O’REGAN 9 MOUNT IDA Spoiled her chance at Cheltenham by jumping to her right throughout and can’t afford the same trait in this company. Should stay if she gets round. ✶✶ 25-1
10 Longhouse Poet, Darragh O'Keeffe: Boasts the ideal profile and latest warm-up effort over hurdles should be forgiven. Had previously won the Thyestes Chase and should enjoy this test. ✶✶✶✶ 16-1
11 Fiddler On The Roof, Brendan Powell: Would need to jump better than at Ascot last time but had previously run a blinder in the Ladbrokes Trophy so was entitled to be rusty. Lively outsider. ✶✶✶✶ 16-1
12 Two For Gold, David Bass: Quirky chaser who is difficult to pass when in the mood. Is often taken to the start early as can boil over and didn’t seem to love these fences in last year’s Topham. ✶✶ 40-1
13 Santini, Nick Schofield: Well handicapped on best efforts and finally gets chance to tackle a marathon trip which should suit a relentless galloper. No surprise to see him outrun his odds. ✶✶✶ 33-1
14 Samcro, Sean Bowen: Mercurial chaser whose career has been derailed by injury and setbacks. Fire still burns, judging by latest Down Royal display, but much more required here. ✶ 66-1
15 Escaria Ten, Adrian Heskin: Chased home Galvin in last season’s National Hunt Chase and looks the type for a marathon trip. Shaped well at Fairyhouse latest and looks a major player. ✶✶✶✶ 11-1
16 Good Boy Bobby, Daryl Jacob: Enjoying a successful season and better than showing at Kempton last time when patiently ridden. Should give a bold sight up front but others preferred at this level. ✶✶ 16-1
2021's winner Minella Times (left) gallops before Saturday's attempt at history
17 Romain De Senam, Phillip Armson: No-show in the Midlands National when a huge price and serious stamina concerns to address, given he is yet to win beyond three miles in a 41-race career. ✶ 80-1
18 Coko Beach,
