Jaguars vs. Commanders prediction, odds, line, spread: 2022 NFL picks, Week 1 best bets from computer model

Jaguars vs. Commanders prediction, odds, line, spread: 2022 NFL picks, Week 1 best bets from computer model
Jaguars vs. Commanders prediction, odds, line, spread: 2022 NFL picks, Week 1 best bets from computer model

New head coach Doug Pederson and the Jacksonville Jaguars have their sights set on notching the franchise's first winning season since coming up just short against the New England Patriots in the 2018 AFC Championship Game. They will open the 2022 NFL season on the road by taking on the Washington Commanders. Washington will once again be breaking in a new starting quarterback in offseason trade acquisition Carson Wentz. Jacksonville will be guided by 2021 No. 1 overall pick Trevor Lawrence. The Commanders are 6-1 all time against the Jaguars.

Washington is favored by 3 points in the latest Jaguars vs. Commanders odds from Caesars Sportsbook, and the over/under is set at 44. Before making any Commanders vs. Jaguars picks, you need to see the NFL predictions and betting advice from the proven model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. The model enters the 2022 NFL season on an incredible 138-97 run on top-rated NFL picks that dates back to the 2017 season. Amazingly, it hasn't missed a top-rated pick since Week 15 last season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Commanders vs. Jaguars and just locked in its picks and NFL Week 1 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Jags vs. Commanders:

Commanders vs. Jaguars spread: Commanders -3 Commanders vs. Jaguars over/under: 44 points Commanders vs. Jaguars picks: See picks here

Featured Game | Washington Commanders vs. Jacksonville Jaguars

Why the Jaguars can cover

The Jaguars hired Pederson with hope that he could work some of his magic on second-year quarterback Lawrence. During his time as head coach of the Eagles, Pederson had Wentz playing at an All-Pro level. Prior to that Pederson had Alex Smith playing Pro Bowl caliber football for the Chiefs.

Second-year running back Travis Etienne is set to make his NFL debut after missing all of his rookie season with a foot injury. The former Clemson star adds an interesting dynamic to the Jacksonville offense with his ability to run between the tackles and catch passes out of the backfield. 

Why the Commanders can cover

Washington rolled the dice on Wentz, and will only go as far as the former No. 2 overall pick can take it. Wentz has proven that he can be a Pro Bowl caliber quarterback, but has struggled mightily in recent years. Wentz does have the added benefit of throwing to one of the NFL's best wide receivers in Terry McLaurin.

Defensively, Washington will undoubtedly miss Chase Young (ACL), who is eligible to return from injured reserve in Week 5. The Commanders still have a stout defensive front with stalwarts Jonathan Allen, Daron Payne, and Montez Sweat.

How to make Commanders vs. Jaguars picks

The model has simulated Commanders vs. Jaguars 10,000 times and the results are in. The model is leaning Under on the total, and it also says one side of the spread has all the value. You can only see the model's pick at SportsLine.

So who wins Jaguars vs. Commanders on Sunday? And which side of the spread holds all the

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