Week 4 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay would pay out 25-1

Week 4 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay would pay out 25-1
Week 4 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay would pay out 25-1

The 2022 NFL schedule has been rife with parity over the first three weeks, as a record 25 games have been decided by six points or fewer. The Las Vegas Raiders (0-3) are one of the two clubs yet to post a victory, but all of their losses were by fewer than seven points. Las Vegas will try to get into the win column when it hosts the AFC West-rival Denver Broncos during the Week 4 NFL schedule. The Raiders are 2.5-point favorites against Denver in the latest Week 4 NFL odds at Caesars Sportsbook, one of the slimmest NFL spreads of the week. Which Week 4 NFL lines should you target with your Week 4 NFL bets? Before you make any Week 4 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 4. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 4 NFL picks at SportsLine

Top Week 4 NFL picks

After simulating every game 10,000 times, the model is high on the Pittsburgh Steelers (-3.5) to win and cover against the New York Jets on Sunday. Pittsburgh has struggled following the retirement of Ben Roethlisberger, as Mitch Trubisky has yet to throw for more than 210 yards and has only two touchdown passes over his first three games. The Steelers are coming off back-to-back losses, but now face a Jets team that has won just one of its nine all-time visits to the Steel City.

New York scored two touchdowns in the final 1:22 of its 31-30 victory at Cleveland in Week 2, but couldn't cross the goal line last Sunday, when it suffered a 27-12 home loss to Cincinnati. The Jets have yet to come up with a strong defensive performance this season, allowing at least 24 points in their three contests. The model expects them to struggle again this week, one reason why Pittsburgh is covering the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 4 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing a pair of underdogs. You can only see the model's NFL Week 4 best bets and parlay at SportsLine

What are the model's top Week 4 NFL picks? And which other NFL matchups should you target for

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