Week 5 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1

Week 5 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1
Week 5 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1

The Dallas Cowboys hope to continue their success without Dak Prescott when they visit the reigning Super Bowl champion Los Angeles Rams during the Week 5 NFL schedule. Dallas (3-1) has posted three consecutive victories with Cooper Rush filling in for Prescott, who fractured his thumb in the season-opener against Tampa Bay. The Rams (2-2) have won three of their last four meetings with the Cowboys, including a victory in the 2018 NFC Divisional playoffs. Los Angeles is a 4.5-point favorite in the latest Week 5 NFL odds at Caesars Sportsbook. Which Week 5 NFL lines should you target with your Week 5 NFL bets? Before you make any Week 5 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 5. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 5 NFL picks at SportsLine

Top Week 5 NFL picks

After simulating every game 10,000 times, the model is high on the Miami Dolphins (-3.5) to win and cover against the New York Jets on Sunday. The Dolphins have won eight of their last nine meetings with the Jets, including the last four. They'll be without quarterback Tua Tagovailoa (concussion) for this matchup, but backup Teddy Bridgewater is 42-21 as a starter in the NFL with a 24-6 record on the road.

New York has struggled at home this season, allowing 51 points while scoring just one touchdown in its two losses. New York quarterback Zach Wilson had a rough time last season in his only career game against Miami, completing only 13-of-23 pass attempts for 170 yard without a touchdown while being sacked six times. That is one reason the Dolphins are covering the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 5 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog to win outright. You can only see the model's NFL Week 5 best bets and parlay at SportsLine

What are the model's top Week 5 NFL picks? And which other NFL matchups should you target for a strong 25-1

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