Dennis Allen and the New Orleans Saints (2-4) will visit State Farm Stadium to play Kliff Kingsbury and the Arizona Cardinals (2-4) on Thursday Night Football. Both teams have stumbled out the gate and will hope to bounce back. In Week 6, New Orleans lost to the Cincinnati Bengals, 30-26. On the opposite sideline, Arizona dropped its matchup against the Seattle Seahawks, 19-9.
Kickoff is set for 8:15 p.m. ET from State Farm Stadium. Arizona is favored by 2.5 points in the latest Saints vs. Cardinals odds from Caesars Sportsbook, and the over/under is 43.5. Before making any Cardinals vs. Saints picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2022 NFL season on an incredible 146-107 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Saints vs. Cardinals and just locked in its picks and TNF predictions. You can visit SportsLine now to see the model's picks. Here are the NFL odds and betting lines for Cardinals vs. Saints:
Saints vs. Cardinals spread: Arizona -2.5 Saints vs. Cardinals over/under: 43.5 points Saints vs. Cardinals money line: New Orleans +122, Arizona -145 NO: Saints are 4-1 ATS in their last five games following a straight-up loss ARI: Under is 5-0 in the Cardinals' last five games Saints vs. Cardinals picks: See picks hereFeatured Game | Arizona Cardinals vs. New Orleans Saints
Arizona has been able to stuff the run and clog holes up front. The Cardinals are currently seventh in the NFL in rushing yards allowed (103.8). Defensive end Zach Allen is playing well to kick off the campaign. Allen gives maximum effort on each play with the strength and explosiveness to shed blocks. The Boston College product has 25 total tackles, four TFLs, five pass deflections, and two sacks.
Defensive end J.J. Watt is an all-around impact player. Watt has great play recognition skills with the awareness to get his hands up at the line of scrimmage. The five-time Pro Bowler can still quickly get off the line and cause havoc in the backfield. Watt is first on the team in sacks (2.5) with four TFLs and three pass deflections. See which team to back here.
Why the Saints can coverNew Orleans owns an extremely talented secondary that is flooded with difference-makers. Safety Tyrann Mathieu is an athletically gifted defender on the backend. Mathieu is constantly around the ball and plays with a feisty edge. The three-time Pro Bowl selection has the speed to break on the ball or deliver a big hit. He's third on the team in total tackles (29) with one interception.
Cornerback Paulson Adebo is a long-armed defender with ball-hawking skills. Adebo understands leverage well with active hands. The Stanford product owns plenty of size (6-foot-1) and has timing to cause knockouts at the catch point. Adebo has 20 total tackles and three pass deflections. See which team to back here.
How to make Saints vs. Cardinals picksSportsLine's model is leaning Over the total, calling for 48 combined points. It also says one side of the spread has all the value. You can only get the model's TNF picks at SportsLine.
So who wins Cardinals vs. Saints on Thursday Night
