Week 12 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1

Week 12 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1
Week 12 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay pays out 25-1

Joe Burrow and the Cincinnati Bengals will visit Derrick Henry and the Tennessee Titans during the Week 12 NFL schedule. The Bengals sit at 6-4 and in second place in the AFC North, while the Titans lead the AFC South at 7-3. Cincinnati enters with the seventh-best offensive yards per game mark at 366.4, even with star receiver Ja'Marr Chase not having played since Week 7 due to a hip injury. Chase is listed as questionable for Week 12, and his return would give the Titans yet another problem to solve. The Bengals are 2.5-point favorites in the latest Week 12 NFL odds at Caesars Sportsbook. Which Week 12 NFL lines should you target with your Week 12 NFL bets? Before you make any Week 12 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 12. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 12 NFL picks at SportsLine.

Top Week 12 NFL picks

After simulating every game 10,000 times, the model is high on the Seattle Seahawks (-4) to cover against the Las Vegas Raiders. It's been a rough year for Las Vegas, and there aren't many reasons to be optimistic that life will improve.

First-year head coach Josh McDaniels had to be reassured that his job was safe following an embarrassing loss to Jeff Saturday and the Colts. He followed that up by needing overtime to outgun the Broncos. The AFC West isn't the softest conference in the NFL, but more was expected from the Raiders, especially after the acquisition of star wide receiver Davante Adams. The offense has been stuck in neutral for most of the season, and the team is now also without tight end Darren Waller and receiver Hunter Renfrow after both were placed on injured reserve. Derek Carr's average yards per game has dropped by nearly 40 points from last season, one reason the Seahawks are covering the spread in over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 12 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that is projected to win outright. You can only see the model's NFL Week 12 best bets and parlay at SportsLine

What are the model's top Week 12 NFL picks? And which other NFL matchups should you target

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