Jean-Claude Juncker, the President of the European Commission, says he notes "with regret" the outcome of the Brexit vote, calling on the UK to say what it plans to do soon.
Ominously, he warns, "Time is almost up."
From CNN's Rob North
The pound has remained stable after Theresa May’s Brexit deal was rejected in a crucial Parliamentary vote on Tuesday evening. It has continued to trade around 1% lower against the dollar, at a level of around 1.27 -- similar to the level it was at before the vote.
Immediately after the historic vote, Theresa May says that given the scale of the defeat, the government will permit a no confidence motion to be debated.
As she sat down, Labour leader Jeremy Corbyn confirmed he had tabled a no confidence vote, which will be heard on Wednesday.
In her brief remarks, May said she would also host discussions with other parties to see how she can find a resolution that would be acceptable to all.
Theresa May's Brexit plan is crushed by 432 votes to 202 -- a record margin.
The big moment has arrived: MPs are voting on the main Brexit agreement struck between British Prime Minister Theresa May and the European Union.
The John Baron Amendment (Amendment F) has been voted down -- by a whopping 600 votes to 24.
Political analyst Carole Walker is joining our panel at Westminster tonight; she filmed this video of the scenes outside Parliament.
After the British PM ended her remarks, the Speaker, John Bercow turned to the proposed amendments on the deal.
However, Labour leader Jeremy Corbyn (Amendment A), the SNP (Amendment K) and Conservative MP Edward Leigh (Amendment B) all declined to move the amendments they had put forward earlier.
The House is now voting on the only remaining amendment.
Here's a recap of what it proposes:
With just one amendment now before the House, the main vote on the Brexit bill itself will come much earlier.
From CNN’s Rob North
The pound has fallen to its lowest level of the day ahead of this crucial Brexit vote.
It is trading at 1.27 against the dollar, down more than 1%. Earlier in the day it had been trading at around 1.29 against the dollar.
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