The Arquettes are an American acting family who have been in show business for three generations. Patriarch Cliff Arquette, born in 1904, was a TV actor and comedian who was known for his persona Charley Weaver, which became so popular that he rarely appeared in public not in character. He married Julie Harrison in 1934 and they divorced in 1942. He had son Lewis Arquette in 1935 with Mildred Nesbitt Le May, however it is unclear what her relationship was with Cliff. Lewis Arquette took after his father and become an actor, as well as a writer and producer. He is known for his roles in Little Nicky, Tango & Cash, The Great Outdoors and starring as J.D. Pickett on The Waltons. He married fellow actress and acting coach Brenda Denaut in 1963, going on to have five children together. The family was based in Chicago before moving to a commune near Arlington, Virginia in the mid 1960s. Patricia Arquette Both Lewis and Brenda died relatively young, with Brenda dying from breast cancer in 1997 and Lewis dying from congestive heart failure in 2001. Rosanna Arquette, 59 Patricia is the eldest of the Arquette siblings, born in New York City in 1959. She is known for starring in Desperately Seeking Susan with Madonna in 1985, as well as After Hours, The Big Blue, Pulp Fiction and Crash. Patricia also has acting and writing credits. Richmond Arquette She has been married four times, first to Anthony Greco in 1979, then James Newton Howard in 1986, followed by John Sidel in 1993. She is currently married to Todd Morgan, tying the knot in 2013. Patricia shares her 24-year-old daughter Zoe Bleu with restaurateur Sidel. Richmond Arquette, 55 Richmond was born in New York City in 1963. He is also an actor, playing minor roles in films such as Zodiac, The Curious Case of Benjamin Button and Fight Club. He was nominated for Best Screenplay at the Northeast Film Festival for co-writing Broken Blood in 2013. Richmond appears to be single. Patrica Arquette, 50 Patricia Arquette Patricia is perhaps the best known actor of her family, starring in several movies and TV series, including True Romance, Ed Wood, Flirting with Disaster, Lost Highway, The Hi-Lo Country, Bringing Out the Dead, Holes and Fast Food Nation. She ran away aged 15 to join her older sister Rosanna and soon began her acting career in 1987 with Pretty Smart. Patricia won the Golden Globe and Oscar for Best Supporting Actress for her role in Boyhood in 2015. She won the Golden Globe for Best Actress – Miniseries or Television Film for Escape at Dannemora this year. Her most recent project is The Act streaming on Hulu and she will also star in Toy Story 4, which is in pre-production. Patricia was just 20 years old when she gave birth to Enzo Rossi in 1989. She shares the son with her musician ex-boyfriend Paul Rossi. She married Nicolas Cage in 1995. The two separated after nine months but kept the news private until Cage filed for divorce in February of 2000. Although they attempted to reconcile and withdrew the divorce petition, Patricia refiled the divorce that November. Her next relationship was with actor Thomas Jane, becoming engaged in 2002. They had their daughter Harlow Olivia Calliope Jane in February 2003. Alexis Arquette They married in Italy in 2006 before filing for divorce in 2009. Although they attempted to work things out, the divorce was finalized in 2011. Alexis, died aged 47 Alexis was born Robert Arquette in Los Angeles in 1969. Alexis was diagnosed with HIV at 16 years old. She later transitioned in 2006. Just like her siblings, she showed a love of the arts early in life. A versatile performer, Alexis got her big break in the 1989 adaptation of Last Exit to Brooklyn where she played the trans sex worker Georgette. She had been visiting New York with her Oscar-winning sister Patricia who was up for a role in the film, but pregnant at the time. She ended up reading and getting the job. Alexis also had small parts in films like Pulp Fiction, Bride of Chucky and as a Boy George impersonator in the Adam Sandler comedy The Wedding Singer and again in Blended. Alexis also performed in nightclubs and cabarets sometimes under the name Eva Destruction. She is credited with being one of the first people to bring increased awareness and visibility to the transgender community, chronicling her transition and the process of her sex reassignment surgery in the 2007 documentary Alexis Arquette: She's My Brother. Alexis revealed in 2016 that she slept with Jared Leto before she transitioned. Family members say Alexis was living as a man at the time of her death. When she died, Alexis was surrounded by all her siblings and loved ones, listening to David Bowie's Starman. At Alexis' wishes, everyone cheered at the moment that Alexis 'transitioned to another dimension.' David Arquette David, 47 David was born in 1971, known for his roles in Scream and marriage to Friends star Courteney Cox. He has more than 120 acting, 19 producing, seven directing and three writing credits to his name. David's first big break came in 1992 when he acted alongside late actor Luke Perry in Buffy the Vampire Slayer. His next big role was in 1996 with Scream, going on to star in three additional movies. He is a professional wrestler, competing in several matches. A longtime admirer of the sport, Arquette starred in the wrestling movie Ready to Rumble in 2000, and became the WCW World Heavyweight Champion during a promotional tour in the same year. He also faced off against WWE Superstar Randy Orton on Monday Night Raw in 2010, where he was slammed through a table. David took part in a bloody death match against former convict Nick Gage, leaving him covered in blood after shards of glass sliced his neck in the match in November 2018. But despite saying he had 'zero plans' to return to the ring after the match, Arquette made a triumphant return to the ring this January. David married Courteney Cox in 1999. Their daughter Coco Arquette was born in 2004, with Jennifer Aniston being the godmother. He and Cox separated in 2010 and they filed for divorce in 2012, which was finalized the next year. During their separation, David began dating Entertainment Tonight correspondent Christina McLarty and the two became pregnant in late 2013, having son Charlie West Arquette in 2014. They married in 2015. They named their second son Augustus Alexis Arquette, in honor of David's late sibling Alexis, when he was born in 2017. David went to rehab in January of 2011 for treatment for 'alcohol and other issues'. After completing rehab, he boasted he had been sober for more than nine months later that year. All rights reserved for this news site dailymail and under his responsibility