Muriel’s Wedding filmmakers reveal how their lives were derailed by their ...

A filmmaking husband and wife duo have given an candid interview about life with their two severely autistic children.

Jocelyn Moorhouse and husband PJ Hogan were at the top of their game in the mid-1990s when they directed the Aussie cult flick Muriel's Wedding. 

They were the toast of Hollywood and found themselves sipping champagne with A-listers and mixing with other top directors. 

'We had really, really made it,' Ms Moorhouse told Australian Story. 'Our careers were successful, our family was perfect - one boy, one girl.' 

But their otherwise perfect lives were totally derailed when their daughter Lily started to display signs of autism.   

Jocelyn Moorhouse and husband PJ Hogan (pictured right and left respectively) were at the top of their game in the mid-1990s when they directed the Aussie cult flick Muriel's Wedding

Jocelyn Moorhouse and husband PJ Hogan (pictured right and left respectively) were at the top of their game in the mid-1990s when they directed the Aussie cult flick Muriel's Wedding

'We had really, really made it,' Moorhouse tells Australian Story. 'Our careers were successful, our family was perfect - one boy, one girl'

'We had really, really made it,' Moorhouse tells Australian Story. 'Our careers were successful, our family was perfect - one boy, one girl' 

Lily was only two when her behaviour started to change. She stopped making eye contact, shunned physical contact and started having screaming fits.

'It was like we had a hurricane in the house,' Lily's brother Spike recalled.

'And we all just had to make the best of taming the hurricane.' 

Lily was diagnosed with severe autism.

Ms Moorhouse, who was the only one who was able to get through to her daughter, was forced to abandon her hugely successful career to care for her. 

After six years of intensive therapy, Lily showed improvements and Ms Moorhouse contemplated going back to work. 

But the couple were about to be dealt a second blow as their 18-month son Jack also began to show signs of

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