World Cup-winning U.S. teammates Michelle Akers and Brandi Chastain announce ...

While the United States national women's soccer team is preparing to face host nation France in the World Cup quarterfinals on Friday, two of the squad's former stars are helping to launch a study into the debilitating brain disease chronic traumatic encephalopathy (CTE).

Teammates on the World Cup-winning U.S. teams in 1991 and 1999, Michelle Akers and Brandi Chastain spoke with CBS This Morning about the long-term study, which focuses on female former soccer players and the possible cognitive effects of the headers and collisions.

Commonly associated with football, hockey and boxing, CTE is caused by repeated hits to the head, and has been connected to everything from memory loss and headaches to depression, dementia and even suicide.

Both Akers and Chastain have admitted to some degree of memory loss, while Akers says she has also battled migraines for years.

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Both Michelle Akers (pictured) and Brandi Chastain have admitted to some degree of memory loss, while Akers says she has also battled migraines for years

Teammates on the World Cup-winning U.S. teams in 1991 and 1999, Michelle Akers and Brandi Chastain (pictured) spoke with CBS This Morning about the long-term study, which focuses on female former soccer players and the possible cognitive effects of the headers and collisions.

Teammates on the World Cup-winning U.S. teams in 1991 and 1999, Michelle Akers (left) and Brandi Chastain (right) spoke with CBS about the long-term study, which focuses on female former soccer players and the possible cognitive effects of the headers and collisions

Akers estimated she endured about 50 headers on game days

Chastain said she was proud to be the player who always managed to head the the ball: 'Oh, I did a lot of heading the ball… And very proudly so and very determined and very aggressive'

Akers (left, against China, in the 1999 World Cup Final) estimated she endured about 50 headers on game days. Chastain (right against Canada in 2000) said she was proud to be the player who always managed to head the ball: 'Oh, I did a lot of heading the ball… And very proudly so and very determined and very aggressive'

'I was the one, the target. So I won every punt by the goalkeepers ... ' said Akers, a former midfielder. 'As far as headers went … usually 50 a game.' 

Chastain, who famously scored the winning penalty kick against China in the 1999 final, had a similar attitude towards head balls during her career: 'Oh, I did a lot of heading the ball… And very proudly so and very determined and very aggressive.'

Now, 20 years later, both players want to know if those head balls contributed to any cognitive issues.

'I can't remember some details of a place we went ... or somebody's last name,' Chastain said. 'But then my friends seem to reassure me that they, too, are experiencing that … So I'm thinking, "Okay, maybe I'm all right."'

'One of the difficulties is, "how do you determine what's not normal and what is?"' Akers asked.

Akers explained she began suspecting there might be a problem after watching a recent documentary on British soccer legend Alan Shearer, who suspected he had early signs of CTE. (A definitive diagnosis can only be made through an autopsy)

'I was watching that and going 'oh my gosh' …' Akers said. 'That could be me … and it stopped me in my tracks.'

The study, which is led by Boston University neurology professor Robert Stern, will follow 20 former high-level women's soccer players who are now over the age of 40. All the former players will be given baseline testing that includes an MRI and a cognitive evaluation.

Akers began suspecting there might be a problem after watching a recent documentary on British soccer legend Alan Shearer (left), who suspected he had early signs of CTE

Akers began suspecting there might be a problem after watching a recent documentary on British soccer legend Alan Shearer (left), who suspected he had early signs of CTE

Soccer obviously isn't known for violent collisions in the way that football and hockey are, but Stern said his fear is repeated sub-concussive trauma – the kind soccer players endure

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