The Florida Department of Health reported 2,488 deaths from COVID-19 over the last seven days - the highest weekly figure since the pandemic began.
But there was also a glimmer of hope for the Sunshine State, as weekly COVID cases dropped by nearly 30,000, sparking hopes that the Delta variant may be on the wane.
The state previously reported 129,202 cases between August 27 and September 2. But figures from Johns Hopkins University released Friday state reported 100,249 cases between September 3 to September 9, News 8 reported.
Johns Hopkins figures put Florida's total deaths at 2,448 between September 3 and September 9. Florida state's report revealed that 353 deaths occurred in the past seven days, although the Sunshine State - which has released figures weekly instead of daily since June - often adds on deaths at a later date.
In the last seven days, on average, the state has added 339 deaths and 15,633 cases to the daily cumulative total, according to the Miami Herald's calculations of a separate set of data from the Centers for Disease Control.
This comes as the US continues to see spikes and drops in daily COVID-19 cases amid the Delta variant, which brought record number of daily cases throughout August, peaking at 322,934.
The U.S. neared the peak again on Friday as Johns Hopkins University & Medicine reported about 262,076 new cases and about 4,409 new deaths.
That figure includes the 2,448 weekly deaths recorded by Florida on Friday.
Despite facing record high COVID-19 deaths, Florida has seen its weekly number of COVID-19 cases drop. This latest week saw cases fall by nearly 300,000
The US saw a recent spike of more than 260,000 new cases reported on Friday
America continues to lead the world in COVID-19 cases since the pandemic first began
The first case of COVID-19 in United States was reported 597 days ago on January 21, 2020, and the nation continues to lead among the countries with the highest number of positive cases at more than 40 million reported.
Florida alone has accounted for nearly 3.5 million cases and reported more than 48,000 deaths so far, according to JHU.
Figures show that 75 per cent of eligible Americans have gotten at least one jab of the vaccine.
Around 56 per cent of those eligible in Florida are fully vaccinated against COVID-19, slightly above the national average of 54 per cent of Americans who are fully inoculated.
Vaccinations across the state saw a significant decline as the state reported more than 518,000 doses administered on the week of August 27, but only 349,845 administered the following week.
This comes as Florida Gov. Mike DeSantis continues to butt heads with President Joe Biden on mask and vaccine mandates.
DeSantis had ordered all schools in the state to not
