The state will be the first to hit the major milestone on Wednesday, with the result to be announced during Thursday's press conference.
NSW recorded 594 new Covid cases in the 24 hours to 8pm on Tuesday, the fewest since August 18.
Ten deaths were also reported which include seven men and three women from Sydney's Covid-hit west and southwestern suburbs, Wollongong, and the Riverina region.
More than 82.2 per cent of eligible residents have received their first Covid-19 jab while 52.7 per cent are now fully vaccinated (pictured, vaccinated Sydneysiders enjoying a picnic)
One person was in their 40s, one person was in their 60s, four people were in their 70s, two people were in their 80s, and two people were in their 90s.
The fatalities bring the state's death toll from the latest outbreak to 395 and the total number since the start of the pandemic to 451.
On Monday restrictions are set to be eased for fully vaccinated people, including five people being allowed