Oxford University researchers uncover gene that doubles risk of death from Covid

Oxford University researchers uncover gene that doubles risk of death from Covid
Oxford University researchers uncover gene that doubles risk of death from Covid

Scientists have discovered a gene common in South Asian people that doubles the risk of death from Covid.

Oxford University researchers found the LZTFL1 gene — present in 60 per cent of South Asians — allows the virus to multiply in the lungs easier.

For comparison, it is only found in 15 per cent of European people and two per cent of black Africans.

Scientists say the genetic quirk may partly explain why South Asian people in the UK have been disproportionately affected by Covid.

But they emphasised the single gene is not the sole reason for the disparity, and highlighted the seriousness of social and economic factors. 

Office for National Statistics data show Bangladeshi men were nearly five times as likely to die with the virus than their white counterparts during the second wave of the pandemic in England. 

Pakistani men were the second most affected (3.4 times as likely), while Indian men were the fourth worst hit ethnic group (1.95 times as likely). 

Scientists have discovered a gene found in 61.2 per cent of people with South Asian ancestry that doubles the risk of death from Covid

Scientists have discovered a gene found in 61.2 per cent of people with South Asian ancestry that doubles the risk of death from Covid

Covid deaths in the second wave were up to five times higher in Bangladeshi Brits than white adults in England, ONS data has shown

Covid deaths in the second wave were up to five times higher in Bangladeshi Brits than white adults in England, ONS data has shown

Figures from the Office for National Statistics (ONS) show fatalities were worst in Black African Britons last spring

Figures from the Office for National Statistics (ONS) show fatalities were worst in Black African Britons last spring

Covid deaths in second wave were up to FIVE TIMES higher in Bangladeshi Brits compared to white adults 

Covid deaths in the second wave were up to five times higher in Bangladeshi Brits than white adults in England, official data revealed today.

Figures from the Office for National Statistics (ONS) show Britons from the 'Black African' demographic group were worst-hit last spring.   

But the trend has changed between the first and second waves, according to the Government's statistical body.

The ONS analysis — which goes up until the end of March — crunched the data of every coronavirus victim aged 30-100 listed on the 2011 census. 

It showed Black African Britons, a group distinct from people with Black Caribbean backgrounds, were 3.7 times more likely to die than white people in the first wave, up to September 11. That dropped to 1.62 in the second wave, considered as starting the day after.

For comparison, the risk among Bangladeshi Brits went from three to 4.96.

The ONS offered no explanation as to why coronavirus deaths were higher in BAME people, or why the second wave hit certain communities harder.

Scientists investigating the topic have repeatedly claimed a number of factors are behind the link, including ethnic minorities being more likely to be key workers who come into contact with more people.

Other included living in crowded housing, where transmission is more likely, as well as having underlying conditions that raise the risk of getting seriously ill. 

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