The victim was assaulted in a house in the Bartley Green area of the city at around 11pm on Saturday.
Nine police cars and an ambulance dashed to Roundlea Road but despite attempts to save the man, he was pronounced dead at the scene.
One resident said: 'The whole street was lit up last night with flashing blue lights.
Police have launched a murder investigation after a man in his 30s was stabbed to death at a Christmas party in Birmingham. Pictured: a cordon remained in place at the home this morning
West Midlands Police say no arrests have been made and asked for witnesses to get in touch
'A friend of mine said he'd heard a young man had been stabbed to death at a house up the road. Apparently there was a bit of a Christmas party going on.
'It's shocking. This area is mostly made up of young families and older people. We rarely get too much trouble. It's worrying when this happens so close to home.'
On Sunday morning police had sealed off the