Some say the Liverpool-born 26-year-old - who appears on The Graham Norton Show tonight - would be a great co-star for Daniel Craig in the as-yet-untitled Bond 25.
Others, meanwhile, reckon she could hold her own as a historic first female iteration of the iconic spy.
Whatever the case, James Bond fans seem enthusiastic about the prospect of her getting involved - as indicated by the bookies' shortening odds.
Earlier this month, Ladbrokes announced that - if Bond were to be female - Comer would be the frontrunner.
She was given odds of 20/1 of replacing Craig; becoming the actress with the shortest odds.
Emily Blunt, perhaps the female who has been the subject of the most 007 talk, is behind on 33/1.
Meanwhile, Emma Watson, Gillian Anderson, Olivia Coleman, Angelina Jolie and Game of Thrones favourites Emilia Clarke and Maisie Williams followed far behind.
"Bond chiefs might make a huge change when Daniel Craig's done with the job, and plenty of punters seem to think a female might get the gig next," a
