Humbled 3-0 by Manchester City on Sunday, Arsenal cannot afford a repeat on Thursday if genuine ambitions still remain to claim a top four spot.
Victory would move Arsene Wenger's side to seven points behind Tottenham in the final Champions League place and provide a glimmer of hope.
Losing again would extinguish the flame and heap further scrutiny on a manager desperately trying to argue he deserves to stay in position in perpetuity.
Sportsmail examines what went wrong at Wembley and how Arsenal could produce a shock win.
Arsenal were humiliated by Manchester City in Sunday's Carabao Cup final at Wembley
The Gunners - 10 points adrift of fourth place - cannot afford another slip-up on Thursday night
Wenger's flirtation with a back-three system in the winter of his career has always seemed at odds with the players at his disposal and the tactics did not work in the League Cup final.
The personnel was significantly different to April's successful FA Cup semi-final, and this time City's wide players pinned Arsenal's full-backs so their attacking potential was nullified.
A 4-2-3-1 formation would create an extra man in midfield and limit the need for another central defender – a position Arsenal have long struggled with.
Sead Kolasinac and Hector Bellerin have enough energy to get up and down the flanks from a more conventional defensive start.
Hector Bellerin has the energy and dynamism to give City problems on the flanks on Thursday
Arsene Wenger surely won't go with a three-man defence again after Sunday's shambles
Whatever the merits of Gary Neville's ultra critical assessment of Arsenal on Sunday, it is undeniable the hunger seemed to be absent all too quickly.
Wigan showed that City are beatable through determined effort, and in particular applying pressure at key moments.
Nobody expects Arsenal's players to run around at full pelt all game, but it was awkward to see some of them walking as City passed the ball around Wembley's wide expanse. Full athletic application is the minimum requirement against a side such as City.
Arsenal were accused of not putting in enough effort