Suffering from mid-life brain fog? It could be due to living it up in your 20s, as study suggests stress, smoking and lack of exercise in youth leads to 'reduced cognitive function' after 40

Suffering from mid-life brain fog? It could be due to living it up in your 20s, as study suggests stress, smoking and lack of exercise in youth leads to 'reduced cognitive function' after 40
By: dailymail Posted On: July 03, 2024 View: 97

It's dubbed the golden decade, when you're meant to be most carefree and at your happiest. 

But being unhealthy in your 20s really could be detrimental to your health years later, US scientists have warned.

Researchers found young adults who smoked, experienced higher levels of stress and rarely exercised were twice as likely to have poor cognitive performance by the time they hit their 40s. 

While some poor cognitive performance is expected with advanced age it can also be precursor to far more serious conditions like dementia.

Dr Kristine Yaffe, an expert in dementia and cognitive ageing at the University of California San Francisco, said: 'Inflammation plays a significant role in cognitive aging and may begin in early adulthood.

Making the most of your 20s really could be detrimental to your health, US scientists warned today. Researchers found young adults who smoked, experienced higher levels of stress and rarely exercised were twice as likely to have poor cognitive performance by the time they hit their 40s

'There is likely a direct and indirect effect of inflammation on cognition.

'Fortunately, there are ways to reduce inflammation — such as by increasing physical activity and quitting smoking — that might be promising paths for prevention.'

Researchers analysed data from more than 2,300 adults aged between 18 and 30-years-old. 

Over a follow-up of 18 years, they were each tested four times for C-reactive protein (CRP), a marker for inflammation.

They then took cognitive tests five years after their last CRP measurement, by which time most participants were in their forties and fifties.

The scientists found just 10 per cent of those with low inflammation scores in their 20s performed poorly on processing speed and memory tests.

But the figure stood at 21 and 19 per cent respectively, among those with either moderate or higher levels, according to the study published in the journal Neurology

'We know from long-term studies that brain changes leading to Alzheimer’s disease and other dementias may take decades to develop,' Dr Amber Bahorik, an expert in psychiatry and cognition at the University of California San Francisco.

'We wanted to see if health and lifestyle habits in early adulthood may play a part in cognitive skills in midlife, which in turn may influence the likelihood of dementia in later life,' she added. 

Around 944,000 people in the UK are thought to be living with dementia, while the figure is thought to be around seven million in the US.

Alzheimer's disease is the most common cause of dementia. The disease can cause anxiety, confusion and short-term memory loss

Alzheimer's is the biggest cause of dementia affecting around six in ten of those with the condition.

It is thought to be caused by a build-up of amyloid and tau in the brain, which clump together and from plaques and tangles that make it harder for the brain to work properly.

Eventually, the brain struggles to cope with this damage and dementia symptoms develop.

The second most common form of dementia is vascular which is where there is a reduced blood flow to the brain such as stroke. 

Memory problems, thinking and reasoning difficulties and language problems are common early symptoms of the condition, which then worsen over time. 

Alzheimer's Research UK analysis found 74,261 people died from dementia in 2022 compared with 69,178 a year earlier, making it the country's biggest killer.

What is Alzheimer's?

Alzheimer's disease is a progressive, degenerative disease of the brain, in which build-up of abnormal proteins causes nerve cells to die.

This disrupts the transmitters that carry messages, and causes the brain to shrink. 

More than 5 million people suffer from the disease in the US, where it is the 6th leading cause of death, and more than 1 million Britons have it.

WHAT HAPPENS?

As brain cells die, the functions they provide are lost. 

That includes memory, orientation and the ability to think and reason. 

The progress of the disease is slow and gradual. 

On average, patients live five to seven years after diagnosis, but some may live for ten to 15 years.

EARLY SYMPTOMS:

  • Loss of short-term memory
  • Disorientation
  • Behavioral changes
  • Mood swings
  • Difficulties dealing with money or making a phone call 

LATER SYMPTOMS:

  • Severe memory loss, forgetting close family members, familiar objects or places
  • Becoming anxious and frustrated over inability to make sense of the world, leading to aggressive behavior 
  • Eventually lose ability to walk
  • May have problems eating 
  • The majority will eventually need 24-hour care   

 Source: Alzheimer's Association

 

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