They've endured more than enough stress throughout the last year after their son Noah, four, was diagnosed with cancer in November.
But Michael Buble and wife Luisana Lopilato enjoyed a rare night out at the premier of the actress' latest movie in Buenos Aires, Argentina, on Monday evening.
The singer, 41, planted a big kiss on his wife's smiling face before exiting the vehicle and hitting the red carpet.
Loving kiss: Michael Buble planted a big kiss on wife Luisana Lopilato at a movie premiere in Buenos Aires, Argentina, on Monday evening
The actress, 30, was beaming with delight as she held on to her beau in the back seat of their car.
Michael sported an all-black ensemble, including a black suit, shirt, tie and shoes, for the night out with his beautiful wife.
The Just Haven't Met You Yet hitmaker added a pop of color to his dark outfit with a silky purple floral pocket square tucked into his chest pocket.
Luisana looked radiant as ever in a long crimson red dress, which featured delicate red straps and cut out panels along the waistline.
All dressed up: The singer, 41, and his actress wife, 30, enjoyed a rare night out at the glamorous film premier
The Fair Market Value star switched between wearing and carrying an exquisite metallic jacket.
The mother-of-two's long blonde hair as swept up and away from her glowing face in elegantly loose finger waves.
Nearly one year ago, the family's world was turned upside down when their youngest son Noah was diagnosed with cancer at just three years old.
The couple canceled both of their work schedules - her film and his tour - as they traveled back and forth from Argentina to Los Angeles for his treatment, bringing along son Elias, 19 months.
Lady in red: Luisana looked radiant as ever in a long crimson red dress, which featured delicated red straps and cut out panels along the waistline
Noah is said to have been treated for liver cancer, although the actress and her husband have never confirmed what type of cancer he was diagnosed with.
In March, the couple were delighted to confirm Noah was 'well'