High-fat food turns off a signal in the brain that tells you when you are full 

Why you crave a second helping: High-fat food turns off a signal in the brain that tells you when you are full, study in mice shows Researchers at Baylor College of Medicine uncovered a previously unknown gut-brain connection Mice consuming a high-fat diet had higher levels of a hormone (called GIP) that manages energy balance But the GIP hormone travels to the brain and inhibits leptin, the hormone that tells you when you are full

By Press Association

Published: 13:31 BST, 13 August 2019 | Updated: 13:32 BST, 13 August 2019

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Listening to your head is not always the answer when it comes to deciding whether or not to go back for second helpings.

A high-fat diet has been linked with turning off the signal in the brain that indicates when you are full.

The study published in the Journal of Clinical Investigation suggests a previously unknown gut-brain connection that helps explain how extra servings lead to weight gain.

Corresponding author Dr Makoto Fukuda, assistant professor of pediatrics at Baylor College of Medicine, said: 'We have uncovered a new piece of the complex puzzle of how the body manages energy balance and affects weight.'

Mice consuming a high-fat diet had higher levels of a hormone (called GIP) that manages energy balance. But the GIP hormone travels to the brain and inhibits leptin, the hormone that tells you when you are full

Mice consuming a high-fat diet had higher levels of a hormone (called GIP) that manages energy balance. But the GIP hormone travels to the brain and inhibits leptin, the

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