By Press Association
Published: 13:31 BST, 13 August 2019 | Updated: 13:32 BST, 13 August 2019
Listening to your head is not always the answer when it comes to deciding whether or not to go back for second helpings.
A high-fat diet has been linked with turning off the signal in the brain that indicates when you are full.
The study published in the Journal of Clinical Investigation suggests a previously unknown gut-brain connection that helps explain how extra servings lead to weight gain.
Corresponding author Dr Makoto Fukuda, assistant professor of pediatrics at Baylor College of Medicine, said: 'We have uncovered a new piece of the complex puzzle of how the body manages energy balance and affects weight.'
Mice consuming a high-fat diet had higher levels of a hormone (called GIP) that manages energy balance. But the GIP hormone travels to the brain and inhibits leptin, the