Saoirse Ronan set social media alight with a powerful reminder about violence against women during an interview on The Graham Norton Show.

The American-born Irish actress, 30, left the all-male panel - which included actors Denzel Washington, Paul Mescal and Eddie Redmayne - in stunned silence after she interjected during a joke about self-defense.

Redmayne, 42, explained that amid his training for The Day of the Jackal, an upcoming Peacock miniseries, he received instruction as how to use a phone to retaliate in the event of an attack.

A guffawing Mescal, 28, added, 'Who is actually going to think about that? If someone actually attacked me, I'm not going to go "phone."'

Giggling Norton, 61, mimicked holding a phone to fend off an assailant, saying, 'Can you hold on a second?' to which Redmayne said, 'That's a very good point.' 

The Oscar-nominated actress then found a moment to share her perspective, saying: 'That's what girls have to think about all the time.'

The brutally honest comment prompted a moment of silence from the panel.

'Am I right, ladies?' she then asked the crowd, eliciting a huge round of applause from the studio audience.

Ronan - who says she would like to play a Bond villain - garnered further plaudits on social media, as people lauded her for speaking up in the situation.

Said one user: 'Saoirse Ronan gagging men we love to see it.'

Another called Ronan 'a queen,' saying that 'men need a reminder what it’s like being a woman so they can appreciate their privilege.

The user noted that 'the silence after she said that speaks volumes,' while another said 'the silence is taking me out.'

A separate user said that the clip 'encapsulates men being ignorant of male privilege in a nutshell.

'The fact that these guys - nice guys, mind - are just so unaware is almost terrifying,' the user said. 'Thank goodness for Saoirse though because we all need a bit more attention drawn to this.'

Said one user: 'I admire Saoirse Ronan so much - when she mentions how women have to think constantly how to defend ourselves from attack and everyone goes quiet and then cheers. She's so right!' 

One user said the moment was a microcosm of how men and women communicate, saying that 'this is what it feels like to have any convo with men ever.'

Another user said that tone deafness in regards to the gender issue was evident in the excerpt from the popular British talk show.

'The thing that angered me the most is that Saoirse Ronan, the only woman on the panel, had to almost fight to make her point amongst a group of laughing men who didn’t consider her input or the experiences of women,' the user said. 'Almost as if that’s the entire f***ing problem isn’t it?' 

Ronan is currently promoting her war drama film Blitz, which is slated to be released in theaters November 1 before streaming on Apple TV+ November 22.

The movie also stars Elliott Heffernan, Harris Dickinson, Benjamin Clémentine, Kathy Burke, Paul Weller and Stephen Graham.

Blitz, written and directed by Steven McQueen, 'follow the stories of a group of Londoners during the events of the British capital bombing in World War II,' a logline for the film reads.

Ronan portrays a woman named named Rita who is raising her son George, nine, (Heffernan) amid the tumultuous time.